VSNexus Technologies

Research

Our research is computational. Each study is pre-registered (hypotheses, seeds, metrics and decision rules are committed before the first evaluation decode), and results are reported whether they confirm the hypothesis or not. Held-out data stays closed until a model passes its development checks.

Topics: sequencing error models and channel simulation; clustering and consensus under insertions and deletions; Reed-Solomon and erasure codes for strand loss; adaptive coverage; benchmarking statistics (Wilson intervals, exact McNemar with Holm correction, paired bootstrap).

Current scientific boundary

Demonstrated computationally

  • Software that encodes files into constraint-screened DNA sequences and recovers them from simulated noisy reads, reporting success only after SHA-256 and Merkle verification.
  • No false success in the decoder evaluations reported from V6 to V9, including 600 paired V9 evaluation cases (SIMULATED).
  • Native C kernels that produce byte-identical results to their Python references, checked with sanitizers and fuzzing.
  • Reproducible experiments: pre-registered designs, committed results files and a reproduction script (29 / 29 rows reproduced at V9).
  • A channel model fitted to public nanopore data, tested against pre-registered criteria and reported as INADEQUATE.

Not demonstrated

  • DNA synthesis, storage, amplification or sequencing of VNX-DNA strands. None has been performed.
  • Performance on real sequencing reads from a physical VNX-DNA experiment.
  • A validated model of any sequencing platform.
  • Storage lifetime, cost per byte, or production readiness.
  • Recovery at coverage 3 under the D13-F1 stress channel, or whole-archive recovery of large archives under it.

Studies

  • V9: consensus V2 and adaptive computational coverage

    Five pre-registered hypotheses on decoding under a nanopore-like stress channel: a native consensus kernel, the oracle gap, a better consensus (candidate E), adaptive coverage, and a latent-class channel model. Four accepted, one rejected.

    Simulated 2026-10-08

  • V7: indel-aware consensus at low coverage

    Full-template consensus confirmed on fresh pre-registered seeds; a low-coverage parity profile reaches 5-read coverage at +42 % strands; below 5 reads the architecture was not sufficient.

    Simulated 2026-10-07

  • V8: fitting a nanopore channel model to public data

    A channel model fitted to the public D13 nanopore dataset reproduces per-base rates and indel run lengths but fails read-level structure tests. Reported as INADEQUATE; held-out data never opened.

    Public data 2026-10-07

Toward physical validation

What a first physical experiment would need. None of this has been done.

  • Synthesis

    An oligo pool ordered from the E15 export package, within the profile's length and constraint limits.

    planned

  • Sequencing

    Illumina and nanopore runs of the same pool, with read files published under an open licence.

    planned

  • Decoding

    Unmodified VNX-DNA decoding of those reads, reported with the same evidence rules as our simulations.

    planned